Aptamers: Applications and Strategies for Development

Aptamers: Applications and Strategies for Development

What are Aptamers? Often described as synthetic antibodies, aptamers are single-stranded DNA or RNA molecules that fold into secondary structures which can bind to target molecules with high affinity and specificity. In 1990, the first aptamer was developed against T4 DNA Polymerase using RNA1. Since then, both aptamer selection methods…